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goat anti sox10  (R&D Systems)


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    Structured Review

    R&D Systems goat anti sox10
    Goat Anti Sox10, supplied by R&D Systems, used in various techniques. Bioz Stars score: 97/100, based on 732 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti+sox10/Human%2FMouse%2FRat+SOX2+Antibody/bio_rxiv__64898__2026__04__15__718827-238-38-42
    Average 97 stars, based on 732 article reviews
    goat anti sox10 - by Bioz Stars, 2026-10
    97/100 stars

    Images

    Related Articles

    Chromatin Immunoprecipitation:

    Article Title: Harnessing 3D collagen hydrogel-directed conversion of human GMSCs into SCP-like cells to generate functionalized nerve conduits
    Article Snippet: .. Materials & experimental systems n/a Involved in the study Antibodies Eukaryotic cell lines Palaeontology and archaeology Animals and other organisms Human research participants Clinical data Dual use research of concern Methods n/a Involved in the study ChIP-seq Flow cytometry MRI-based neuroimaging Antibodies Antibodies used For IF: mouse anti-p75 (5 μg/mL, Sigma, St. Louis, Missouri, USA), rabbit anti-SOX-9 (5μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-HES1 (5μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), mouse anti-SOX10 (5μg/mL, R & D System, Minneapolis, Minnesota, USA), rabbit anti-S-100beta (5μg/mL, Boster Biological Tech, Pleasanton, California), rabbit antiNotch3 (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), rabbit anti-BDNF (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), rabbit anti-GDNF (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), rabbit anti-NGF (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), mouse anti-vinculin (5 μg/mL, Sigma, St. Louis, Missouri, USA), TRITC-phalloidin (0.5 μg/mL, Sigma, St. Louis, Missouri, USA), mouse anti-neurofilament (5μg/mL, BioLegend, San Diego, California, USA), goat anti-rabbit IgG, Alexa Fluor 488, goat anti-rabbit IgG, Alexa Fluor 594, goat anti-mouse IgG, Alexa Fluor 488, goat anti-mouse IgG, Alexa Fluor 594, or normal anti-rabbit, normal anti-mouse IgG, Alexa Fluor 488 , Alexa Fluor 594 (2.5 μg/mL, BioLegend, San Diego, California, USA). .. For Western blot: rabbit anti-p75 (1μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-HES1 (1μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-GAPDH (1 μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-Notch3 (1μg/mL, Abcam, Cambridge, Massachusetts, USA).

    Flow Cytometry:

    Article Title: Harnessing 3D collagen hydrogel-directed conversion of human GMSCs into SCP-like cells to generate functionalized nerve conduits
    Article Snippet: .. Materials & experimental systems n/a Involved in the study Antibodies Eukaryotic cell lines Palaeontology and archaeology Animals and other organisms Human research participants Clinical data Dual use research of concern Methods n/a Involved in the study ChIP-seq Flow cytometry MRI-based neuroimaging Antibodies Antibodies used For IF: mouse anti-p75 (5 μg/mL, Sigma, St. Louis, Missouri, USA), rabbit anti-SOX-9 (5μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-HES1 (5μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), mouse anti-SOX10 (5μg/mL, R & D System, Minneapolis, Minnesota, USA), rabbit anti-S-100beta (5μg/mL, Boster Biological Tech, Pleasanton, California), rabbit antiNotch3 (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), rabbit anti-BDNF (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), rabbit anti-GDNF (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), rabbit anti-NGF (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), mouse anti-vinculin (5 μg/mL, Sigma, St. Louis, Missouri, USA), TRITC-phalloidin (0.5 μg/mL, Sigma, St. Louis, Missouri, USA), mouse anti-neurofilament (5μg/mL, BioLegend, San Diego, California, USA), goat anti-rabbit IgG, Alexa Fluor 488, goat anti-rabbit IgG, Alexa Fluor 594, goat anti-mouse IgG, Alexa Fluor 488, goat anti-mouse IgG, Alexa Fluor 594, or normal anti-rabbit, normal anti-mouse IgG, Alexa Fluor 488 , Alexa Fluor 594 (2.5 μg/mL, BioLegend, San Diego, California, USA). .. For Western blot: rabbit anti-p75 (1μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-HES1 (1μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-GAPDH (1 μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-Notch3 (1μg/mL, Abcam, Cambridge, Massachusetts, USA).

    Magnetic Resonance Imaging:

    Article Title: Harnessing 3D collagen hydrogel-directed conversion of human GMSCs into SCP-like cells to generate functionalized nerve conduits
    Article Snippet: .. Materials & experimental systems n/a Involved in the study Antibodies Eukaryotic cell lines Palaeontology and archaeology Animals and other organisms Human research participants Clinical data Dual use research of concern Methods n/a Involved in the study ChIP-seq Flow cytometry MRI-based neuroimaging Antibodies Antibodies used For IF: mouse anti-p75 (5 μg/mL, Sigma, St. Louis, Missouri, USA), rabbit anti-SOX-9 (5μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-HES1 (5μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), mouse anti-SOX10 (5μg/mL, R & D System, Minneapolis, Minnesota, USA), rabbit anti-S-100beta (5μg/mL, Boster Biological Tech, Pleasanton, California), rabbit antiNotch3 (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), rabbit anti-BDNF (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), rabbit anti-GDNF (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), rabbit anti-NGF (2.5μg/mL, Abcam, Cambridge, Massachusetts, USA), mouse anti-vinculin (5 μg/mL, Sigma, St. Louis, Missouri, USA), TRITC-phalloidin (0.5 μg/mL, Sigma, St. Louis, Missouri, USA), mouse anti-neurofilament (5μg/mL, BioLegend, San Diego, California, USA), goat anti-rabbit IgG, Alexa Fluor 488, goat anti-rabbit IgG, Alexa Fluor 594, goat anti-mouse IgG, Alexa Fluor 488, goat anti-mouse IgG, Alexa Fluor 594, or normal anti-rabbit, normal anti-mouse IgG, Alexa Fluor 488 , Alexa Fluor 594 (2.5 μg/mL, BioLegend, San Diego, California, USA). .. For Western blot: rabbit anti-p75 (1μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-HES1 (1μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-GAPDH (1 μg/mL, Cell Signaling Tech, Danvers, Massachusetts, USA), rabbit anti-Notch3 (1μg/mL, Abcam, Cambridge, Massachusetts, USA).

    Blocking Assay:

    Article Title: Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease
    Article Snippet: .. Fixed cells were blocked with blocking solution (1% BSA, 0.1% Triton X-100 in PBS) at room temperature for 1 h. The blocked cells were then incubated with primary antibodies (mouse anti-SOX10 [1:500, R&D Systems MAB2864], rabbit anti-TUJ1 [1:1000, Abcam ab18207] and mouse anti-HU [1:1000, Thermo Fisher Scientific A-21271]) at 4°C overnight. .. After washing, the sections were incubated with respective secondary antibodies conjugated with Alexa Fluor 488/594 (Thermo Fisher Scientific 1:500) at room temperature for 2 h. The stained cells were mounted with ProLong Diamond Antifade Mountant with DAPI (Thermo Fisher Scientific).

    Incubation:

    Article Title: Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease
    Article Snippet: .. Fixed cells were blocked with blocking solution (1% BSA, 0.1% Triton X-100 in PBS) at room temperature for 1 h. The blocked cells were then incubated with primary antibodies (mouse anti-SOX10 [1:500, R&D Systems MAB2864], rabbit anti-TUJ1 [1:1000, Abcam ab18207] and mouse anti-HU [1:1000, Thermo Fisher Scientific A-21271]) at 4°C overnight. .. After washing, the sections were incubated with respective secondary antibodies conjugated with Alexa Fluor 488/594 (Thermo Fisher Scientific 1:500) at room temperature for 2 h. The stained cells were mounted with ProLong Diamond Antifade Mountant with DAPI (Thermo Fisher Scientific).



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    A Phase-contrast images showing control human SC ( cSC ) and patient-derived SC ( pdSC ) cultures at DIV7. B Immunocytochemistry staining of <t>SOX10</t> (magenta) and S100B (orange) in control human SC ( cSC ), patient-derived SC ( pdSC ) and fibroblast ( Fibroblast _1) cell cultures at DIV7. Nuclei were stained with DAPI (grey). Scale bar: 100 µm. C Gene expression of <t>SOX10,</t> S100B , and MBP in pdSCs ( n = 6), and cSCs ( n = 3). Median ± range. *, p < 0.05.
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    Santa Cruz Biotechnology mouse anti sox10 antibody
    a UMAP projection displaying thalamic clusters. Tha_ExN_CALB population corresponds to PVT neurons, with 97.4% of cells classified within ExN_CALB in Fig. . b Left: Proportional distribution of thalamic cell clusters, comparing BD and control. Total nuclei counts are normalized to 10,000, and the total nuclei count in BD and control is adjusted to an equivalent sum. Right: Compositional changes estimated by sccomp with log2(Fold-change) on the x-axis and -log10(FDR) on the y-axis. Circle size reflects the number of nuclei per cluster, and color denotes major cell classes. c Cell density (cell count per 100 mm 2 ) of excitatory neurons and oligodendrocytes in BD and control by immunohistochemistry. The unadjusted two-sided p-values and fold-changes estimated by GLM are indicated. d Representative images of immunohistochemistry of CT10 and BT15 using VGLUT2 and <t>SOX10</t> for excitatory neurons and oligodendrocytes. Immunohistochemical analyses were performed on samples from 19 patients with BD and 17 control individuals. e DEG and DEG-GO count across thalamic clusters. f Downregulated (left) and upregulated (right) robust DEG-GOs. The x-axis denotes fold-change, and the y-axis reflects the robustness score. Circle size represents the number of DEGs within the GO term, and color indicates the respective cell cluster. Among robust DEGs, only enriched GO terms among possible DEGs are displayed for fold-change calculation. Source data are provided as a file.
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    Image Search Results


    A Phase-contrast images showing control human SC ( cSC ) and patient-derived SC ( pdSC ) cultures at DIV7. B Immunocytochemistry staining of SOX10 (magenta) and S100B (orange) in control human SC ( cSC ), patient-derived SC ( pdSC ) and fibroblast ( Fibroblast _1) cell cultures at DIV7. Nuclei were stained with DAPI (grey). Scale bar: 100 µm. C Gene expression of SOX10, S100B , and MBP in pdSCs ( n = 6), and cSCs ( n = 3). Median ± range. *, p < 0.05.

    Journal: Communications Biology

    Article Title: Culture and gene expression profiling of Schwann cells from human sural nerve

    doi: 10.1038/s42003-026-11023-z

    Figure Lengend Snippet: A Phase-contrast images showing control human SC ( cSC ) and patient-derived SC ( pdSC ) cultures at DIV7. B Immunocytochemistry staining of SOX10 (magenta) and S100B (orange) in control human SC ( cSC ), patient-derived SC ( pdSC ) and fibroblast ( Fibroblast _1) cell cultures at DIV7. Nuclei were stained with DAPI (grey). Scale bar: 100 µm. C Gene expression of SOX10, S100B , and MBP in pdSCs ( n = 6), and cSCs ( n = 3). Median ± range. *, p < 0.05.

    Article Snippet: Samples were then incubated with the primary antibodies monoclonal mouse to SOX10 (1:50, #SC-365692, Santa Cruz, RRID: AB_10844002), monoclonal rabbit to S100B (1:500, #ab52642, Abcam, RRID:AB_882426), monoclonal rat to MBP (1:100, #ab7349, Abcam, RRID:AB_305869) and/or monoclonal mouse to FN1 (1:100, #SC-8422, Santa Cruz, RRID: AB_627598) in 1% FBS/0.1% Triton/PBS over night at 4 °C.

    Techniques: Phase Contrast, Control, Derivative Assay, Immunocytochemistry, Staining, Gene Expression

    a UMAP projection displaying thalamic clusters. Tha_ExN_CALB population corresponds to PVT neurons, with 97.4% of cells classified within ExN_CALB in Fig. . b Left: Proportional distribution of thalamic cell clusters, comparing BD and control. Total nuclei counts are normalized to 10,000, and the total nuclei count in BD and control is adjusted to an equivalent sum. Right: Compositional changes estimated by sccomp with log2(Fold-change) on the x-axis and -log10(FDR) on the y-axis. Circle size reflects the number of nuclei per cluster, and color denotes major cell classes. c Cell density (cell count per 100 mm 2 ) of excitatory neurons and oligodendrocytes in BD and control by immunohistochemistry. The unadjusted two-sided p-values and fold-changes estimated by GLM are indicated. d Representative images of immunohistochemistry of CT10 and BT15 using VGLUT2 and SOX10 for excitatory neurons and oligodendrocytes. Immunohistochemical analyses were performed on samples from 19 patients with BD and 17 control individuals. e DEG and DEG-GO count across thalamic clusters. f Downregulated (left) and upregulated (right) robust DEG-GOs. The x-axis denotes fold-change, and the y-axis reflects the robustness score. Circle size represents the number of DEGs within the GO term, and color indicates the respective cell cluster. Among robust DEGs, only enriched GO terms among possible DEGs are displayed for fold-change calculation. Source data are provided as a file.

    Journal: Nature Communications

    Article Title: Disturbances of paraventricular thalamic nucleus neurons in bipolar disorder revealed by single-nucleus analysis

    doi: 10.1038/s41467-025-68094-5

    Figure Lengend Snippet: a UMAP projection displaying thalamic clusters. Tha_ExN_CALB population corresponds to PVT neurons, with 97.4% of cells classified within ExN_CALB in Fig. . b Left: Proportional distribution of thalamic cell clusters, comparing BD and control. Total nuclei counts are normalized to 10,000, and the total nuclei count in BD and control is adjusted to an equivalent sum. Right: Compositional changes estimated by sccomp with log2(Fold-change) on the x-axis and -log10(FDR) on the y-axis. Circle size reflects the number of nuclei per cluster, and color denotes major cell classes. c Cell density (cell count per 100 mm 2 ) of excitatory neurons and oligodendrocytes in BD and control by immunohistochemistry. The unadjusted two-sided p-values and fold-changes estimated by GLM are indicated. d Representative images of immunohistochemistry of CT10 and BT15 using VGLUT2 and SOX10 for excitatory neurons and oligodendrocytes. Immunohistochemical analyses were performed on samples from 19 patients with BD and 17 control individuals. e DEG and DEG-GO count across thalamic clusters. f Downregulated (left) and upregulated (right) robust DEG-GOs. The x-axis denotes fold-change, and the y-axis reflects the robustness score. Circle size represents the number of DEGs within the GO term, and color indicates the respective cell cluster. Among robust DEGs, only enriched GO terms among possible DEGs are displayed for fold-change calculation. Source data are provided as a file.

    Article Snippet: Mouse anti-SOX10 antibody (Santa Cruz #sc-365692A-2) and rabbit anti-VGLUT2 (Synaptic Systems #135403) were applied at dilutions of 1:250 and 1:750, respectively, for 32 min at 37 °C.

    Techniques: Control, Cell Characterization, Immunohistochemistry, Immunohistochemical staining